William C Cushman Selected Research

Chlorthalidone (Chlortalidone)

1/2022	Design of a pragmatic clinical trial embedded in the Electronic Health Record: The VA's Diuretic Comparison Project.
10/2019	Association of orthostatic hypertension with mortality in the Systolic Hypertension in the Elderly Program.
11/2018	Comparison of Effectiveness of Azilsartan Medoxomil and Olmesartan in Blacks Versus Whites With Systemic Hypertension.
1/2018	A randomized titrate-to-target study comparing fixed-dose combinations of azilsartan medoxomil and chlorthalidone with olmesartan and hydrochlorothiazide in stage-2 systolic hypertension.
1/2018	The Effects of eGFR Change on CVD, Renal, and Mortality Outcomes in a Hypertensive Cohort Treated With 3 Different Antihypertensive Medications.
9/2017	Comparison of long-term safety of fixed-dose combinations azilsartan medoxomil/chlorthalidone vs olmesartan medoxomil/hydrochlorothiazide.
4/2017	Treatment-Resistant Hypertension and Outcomes Based on Randomized Treatment Group in ALLHAT.
1/2017	Association of 3 Different Antihypertensive Medications With Hip and Pelvic Fracture Risk in Older Adults: Secondary Analysis of a Randomized Clinical Trial.
12/2016	Electrocardiographic measures of left ventricular hypertrophy in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.
11/2014	Stroke outcomes among participants randomized to chlorthalidone, amlodipine or lisinopril in ALLHAT.

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William C Cushman Research Topics

Disease

40	Hypertension (High Blood Pressure) 01/2022 - 01/2002
39	Type 2 Diabetes Mellitus (MODY) 01/2022 - 01/2002
39	Myocardial Infarction 01/2021 - 11/2002
27	Stroke (Strokes) 01/2022 - 11/2003
27	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 11/2002
24	Heart Failure 01/2022 - 11/2002
11	Acute Coronary Syndrome 10/2018 - 10/2011
7	Isolated Systolic Hypertension 10/2019 - 03/2002
7	Coronary Disease (Coronary Heart Disease) 01/2017 - 11/2002
6	Chronic Renal Insufficiency 01/2021 - 05/2003
6	Diabetes Mellitus 01/2020 - 04/2009
5	Unstable Angina 11/2020 - 10/2013
4	Hypotension (Low Blood Pressure) 01/2021 - 11/2015
4	Acute Kidney Injury (Acute Renal Failure) 01/2021 - 11/2015
4	Syncope (Fainting) 01/2021 - 11/2015
3	Hypoglycemia (Reactive Hypoglycemia) 01/2021 - 03/2011
3	Kidney Diseases (Kidney Disease) 01/2021 - 03/2016
3	Orthostatic Hypotension (Postural Hypotension) 01/2021 - 10/2016
3	Prediabetic State (Prediabetes) 01/2021 - 08/2017
3	Essential Hypertension 01/2018 - 12/2012
3	Chronic Kidney Failure (Chronic Renal Failure) 01/2018 - 05/2009
3	Obesity 02/2017 - 05/2003
2	Atrial Fibrillation 01/2022 - 10/2017
2	Neoplasms (Cancer) 01/2022 - 10/2013
2	Bradycardia 01/2021 - 01/2020
2	Overweight 02/2017 - 02/2017
2	Peripheral Arterial Disease 11/2014 - 09/2006
2	Hypokalemia 12/2012 - 05/2012
2	Albuminuria 05/2012 - 08/2010
2	Dyslipidemias (Dyslipidemia) 07/2010 - 06/2007
2	Sleep Apnea Syndromes (Sleep Apnea) 06/2008 - 06/2008
1	Atrial Flutter (Flutter, Atrial) 01/2022
1	Erectile Dysfunction 01/2021
1	Vascular Diseases (Vascular Disease) 01/2021
1	Cognitive Dysfunction 01/2020
1	Ischemic Stroke 01/2020
1	Body Weight (Weight, Body) 01/2018
1	Headache (Headaches) 09/2017
1	Nasopharyngitis 09/2017
1	Dizziness (Lightheadedness) 09/2017
1	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 12/2016
1	Chronic Disease (Chronic Diseases) 11/2015

Drug/Important Bio-Agent (IBA)

49	Antihypertensive Agents (Antihypertensives)IBA 12/2021 - 03/2002
31	LipidsIBA 10/2017 - 11/2002
25	Chlorthalidone (Chlortalidone)FDA LinkGeneric 01/2022 - 11/2002
22	DiureticsIBA 01/2022 - 11/2002
20	Amlodipine (Norvasc)FDA LinkGeneric 01/2018 - 01/2002
19	Lisinopril (Prinivil)FDA LinkGeneric 01/2018 - 11/2002
15	ThiazidesIBA 01/2022 - 05/2003
14	Hydrochlorothiazide (Esidrix)FDA LinkGeneric 01/2022 - 10/2005
13	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2017 - 11/2002
12	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 06/2005
11	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 01/2017 - 11/2002
9	dulaglutideIBA 01/2022 - 01/2018
9	alogliptinIBA 08/2018 - 10/2011
8	Pharmaceutical PreparationsIBA 01/2021 - 05/2003
5	Hypoglycemic Agents (Hypoglycemics)IBA 01/2020 - 10/2011
5	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2020 - 01/2018
5	azilsartan medoxomilIBA 11/2018 - 08/2012
5	Doxazosin (Cardura)FDA LinkGeneric 02/2013 - 11/2002
4	omega-Chloroacetophenone (Mace)IBA 01/2021 - 05/2015
4	ElectrolytesIBA 01/2021 - 11/2015
4	IncretinsIBA 11/2020 - 01/2018
4	Angiotensin Receptor AntagonistsIBA 11/2018 - 05/2003
4	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 05/2017 - 06/2008
4	Sodium Chloride Symporter Inhibitors (Diuretics, Thiazide)IBA 01/2017 - 12/2003
4	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2016 - 10/2011
4	Irbesartan FDA LinkGeneric 01/2008 - 10/2005
3	hydroxide ionIBA 01/2021 - 10/2016
3	Glucagon-Like Peptide-1 ReceptorIBA 11/2020 - 01/2019
3	Insulin (Novolin)FDA Link 01/2020 - 05/2017
3	Blood Glucose (Blood Sugar)IBA 01/2020 - 08/2010
3	olmesartanIBA 11/2018 - 08/2012
3	CreatinineIBA 09/2017 - 08/2010
3	Valsartan (Vals)FDA Link 04/2012 - 08/2011
2	Glucagon-Like Peptide-1 Receptor AgonistsIBA 01/2021 - 01/2021
2	Retinaldehyde (Retinal)IBA 01/2018 - 08/2010
2	Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA 01/2018 - 10/2013
2	CholesterolIBA 02/2017 - 02/2017
2	SodiumIBA 11/2016 - 08/2012
2	Simvastatin (Zocor)FDA LinkGeneric 07/2010 - 04/2010
2	Fenofibrate (CiL)FDA LinkGeneric 07/2010 - 04/2010
2	Fibric Acids (Fibrates)IBA 04/2010 - 06/2007
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 04/2010 - 06/2007
2	Drug CombinationsIBA 06/2008 - 06/2008
2	Losartan (Cozaar)FDA LinkGeneric 11/2003 - 03/2002
1	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2021
1	Metformin (Glucophage)FDA LinkGeneric 01/2021
1	3,5-diisopropylsalicylic acid (DIPS)IBA 01/2019
1	welan (S 130)IBA 10/2018
1	Olmesartan Medoxomil (Votum)FDA Link 09/2017
1	Troponin IIBA 05/2017
1	dipeptidaseIBA 05/2016

Therapy/Procedure

38	Therapeutics 01/2021 - 11/2002
7	Glycemic Control 01/2021 - 06/2007
3	Subcutaneous Injections 01/2019 - 01/2018
2	Light Coagulation 08/2010 - 07/2010
2	Vitrectomy 08/2010 - 07/2010
1	Injections 01/2018
1	Activities of Daily Living (ADL) 11/2015